A new study reveals the role of STAP-1 in T cell activation and immune response, showing its mediation in cell signaling and its potential link to immune disorders like multiple sclerosis and asthma. This understanding paves the way for therapeutic advancements targeting STAP-1. Credit: SciTechDaily.com The inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO mice exhibited less demyelination—loss of the myelin sheath that surrounds nerves—when compared with those of WT mice (bottom panels). Credit: Kota Kagohashi, et al. The Journal of Immunology. February 5, 2024
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